The researchers behind the new study aimed to find the optimal balance between the amount of caffeine and the time it’s administered. To do so, they used data from four past caffeine-sleep studies and inputted them into an algorithm built on the unified model of performance, which is a mathematical model that accurately predicts the effects of sleep–wake schedules and caffeine consumption on simple neurobehavioral tasks.
The team, led by the U.S. Army Medical Research and Materiel Command’s Dr. Jaques Reifman, ran thousands of simulations across a wide range of doses and sleep-wake schedules.
“We found that by using our algorithm, which determines when and how much caffeine a subject should consume, we can improve alertness by up to 64 percent, while consuming the same total amount of caffeine,” Reifman told Science Daily. “Alternatively, a subject can reduce caffeine consumption by up to 65 percent and still achieve equivalent improvements in alertness.”
The algorithm could someday be used, for instance, by college students who want to know when they should consume caffeine “so you are as alert as possible during the exam,” Reifman told Live Science.
The optimal caffeine dose amounts and times depended on each individual scenario, so there’s no universal recommendation for when and much caffeine to consume. However, the U.S. Army is reportedly using the algorithm in experiments with soldiers in an effort to improve sleep health in the military, an organization in which sleep deprivation is a constant and often unavoidable problem.
The base algorithm looks like this:

If that’s not your cup of joe, a simplified version of the algorithm is available to the public through the 2B-Alert app, which lets users enter their sleep schedules and caffeine intake to find out when and how much caffeine they should consume.
Source: Big Think
Hints of a ghosty, “sterile” version of the neutrino:
The best way to explore “last-of-their-kind patches” might be in the pages of storybooks, or in the chapters of our imagination:
‘The list of serial killers who wore glasses is long and bloody, from Dahmer to BTK to Harold Shipman and his professorial frames; even the Zodiac Killer, never caught, wears a thick-rimmed pair in a police sketch. The aesthetic of “serial killer glasses” is so pervasive that it pops up everywhere from Urban Dictionary (“Eyeglasses with heavy or severe frames that live somewhere between fashionable and creepy”) to TV Tropes (where “a guy who is cold, emotionless … or even a soulless monster” is given glasses “to quickly tip off the audience to his personality”), and countless Tumblr posts in between.
Tali Sharot and Neil Garrett:
No so fast:
‘…Trump’s inner circle has solidified, and the president is increasingly acting on his own. Meetings are getting smaller, reducing the number of people with proximity to information. Top officials, some who acted as relatively helpful press gatekeepers, like former communications director Hope Hicks, have left without replacements. And, after back-and-forth hostile leaks between the White House and State Department under Rex Tillerson, reporters are now dealing with National Security Adviser John Bolton and Secretary of State Mike Pompeo, kindred spirits who are also more discreet.
Sam Hobson is a wildlife photographer with a twist. His focus is on the ‘invasive’ species that are colonizing urban spaces, e.g. red foxes (I have a family living on my street outside of Boston) and parakeets (whose populations are burgeoning in the air over cities like London, some say thanks to Jimi Hendrix releasing a mating pair sometime around 50 years ago to make the city more colorful!). Such arresting images often require painstaking groundwork.
The recent drop in fertility brings the U.S. more in line with peer countries:
Former federal prosecutor Nelson Cunningham in
‘On the eve of his 89th birthday, one of the world’s most influential living thinkers is looking spry as he offers his view on the most pressing issues of our time from his home in Starnberg, including nationalism, immigration, the internet and Europe…’
‘New
Via
‘Animal rights activists have done stellar work in foregrounding the question of creature-consciousness: no meat-eater is now ignorant of the fact that their food once lived, breathed, maybe nuzzled its kin in a blood-soaked slaughterhouse. Environmentalists have a harder go of it. Fracking footage will always be less upsetting than your average fast food expose: Plants, after all, can’t wail frantically as they’re mowed down by the millions. But does that mean they’re not conscious? Is it sensible, or desirable, to start anthropomorphizing crabgrass and dandelions, or are plants really as insensitive as we all instinctively assume?…’
‘White people have called the police on black people in multiple incidents recently, despite no crimes being committed. Professor Khalil Muhammad thinks it’s a problem with a complex history….’
New Laurence Tribe Book Offers Cautions:
In a companion piece, Frum catalogues the open questions about potential criminal acts by the Buffoon-in-Chief, his campaign, his company, and his family. However, he cautions that all he has to do to avoid repercussions is tell lies his contemptibly credulous base believes:
‘Things look pretty bleak for the northern white rhinoceros. Since the death of Sudan, the last male, the entirety of the subspecies has dwindled to only two females. But a group of scientists is churning away on a high-tech save involving carefully cryopreserved cells and tissue cultures from long-dead northern white rhinos. And a new study on the genetics of these precious samples suggests that they are diverse enough to successfully seed a recovered population in the future….’
Bernard Schiff, professor emeritus of psychology at the University of Toronto and former publisher of The Walrus:
And what we can do about it
If the famous cryptid is real, this hunt ought to find it—but if not, scientists will still gain valuable ecological data.
‘This video is real, but good luck convincing your brain that those sounds are coming from a wildcat and not from a 46-year-old man in existential anguish….’
The only variable that can explain the high rate of mass shootings in America is its astronomical number of guns.
e Life Of One Of America’s Bloodiest Hitmen
T. M. Luhrmann writes:
‘When a massive star expends its fuel, its core collapses into a dense object and sends the rest of its gas outward in an event called a supernova. What’s left is mostly neutron stars or black holes. And now, Hubble seems to have seen a supernova blink out — suggesting it captured the moment when a black hole took over.
Robert Wright reflecting on the intellectual feud between Harris and Ezra Klein:
Christopher Nolan brought a restored print — although he prefers to call it ‘unrestored’ to emphasize its fidelity to Kubrick’s original vision and intent — to Cannes. In this interview he waxes enthusiastic about the mindbending film, which he first saw at age 7 when it was rereleased in 70 mm.
Hardly the first time the enfant terrible has spoken in racially fraught terms about immigrants:
‘Evidence of the octopus evolution show it would have happened too quickly to have begun here on Earth. Published in the Progress in Biophysics and Molecular Biology Journal, 33 scientists have declared the invertebrate sea-dweller an alien whose eggs landed from space….’
—and When to Vote Them Out
‘People living in tick-endemic areas around the world are being warned of an increasingly prevalent, potentially life-threatening side effect to being bitten: developing a severe allergy to meat.
Researchers from Took University show that the human visual system has the ability to perceive objects beyond the limits of our visual field.
Nearly unanimous:
‘…Trump’s nominee for CIA director is facing a tough confirmation hearing before the Senate Intelligence Committee Wednesday over her controversial role in the Bush-era torture program.
In one word:
‘What kind of people are most likely to return a lost wallet to its owner? One man went to some pretty extreme lengths to find out….’
Look to the gut:
Jeremy Shapiro writes:
I have always learned that, since the word processor supplanted the typewriter, that it was wrong to persist with the time-honored practice of two-space sentence separations. But I never quite understood the argument for one-spacing. Now a group of Skidmore College psychological researchers, in a study published in Attention, Perception and Psychophysics, prove reading is more efficient, albeit only slightly so, if sentences are more separated. I might very well go back to two spaces after periods. (If you were wondering, two-spacing after commas was not beneficial, and indeed slowed down reading speed.) Ironically, the study was submitted to the journal two-spaced, but the journal’s proofreaders deleted all the extra spaces.
‘Science-fiction writers have fantasised about virtual reality (VR) for decades. Now it is here – and with it, perhaps, the possibility of the complete physical experience of killing someone, without harming a soul. As well as Facebook’s ongoing efforts with Oculus Rift, Google recently bought the eye-tracking start-up Eyefluence, to boost its progress towards creating more immersive virtual worlds. The director Alejandro G Iñárritu and the cinematographer Emmanuel Lubezki, both famous for Birdman (2014) and The Revenant (2015), have announced that their next project will be a short VR film.
We may live in a multiverse checkered with black holes, each containing its own universe… It all centers around a different theory of what exactly a black hole is. The general understanding is nothing can escape a black hole’s intense gravity, not even light. Called the black hole information paradox, it’s thought that even the information about an object that gets sucked in vanishes into oblivion. But therein lies a problem….’
How Could This Impact the Human Mind?
Trump’s Doctor Says Trump Dictated 2015 Letter Saying He’d Be the Healthiest President Ever
Last night, Walpurgis night, the eve of the Saint’s Day for Walpurga, an 8th century abbess in Francia canonized for battling witches, was the time of the Witches’ Sabbaths at the tops of wild remote mountains (most famously, the Brocken, the highest peak in the Harz Mountains in central Germany, as memorialized in Goethe’s Faust) to cavort with the Devil. The attendants ride flying goats, trample the cross and are rebaptized in the name of the Devil. Magic ointments made from Deadly Nightshade (Belladonna), Henbane, Mandrake, Datura or the fly agaric mushroom evoke weird hallucinations and place participants in an altered state of consciousness, conferring the powers of flight and of shapeshifting. Walpurgisnacht also entails a procession of the dead, especially those who have died prematurely or violently during the past year and have been wandering to expiate their sins.
Kelly thinks he’s saving U.S. from disaster:
‘Sarah Huckabee Sanders can dish it, but Republicans can’t take it….’
City Upbringing, Without Pets, Increases Risk of Mental Illness
‘With meth resurgent and the opioid crisis showing no sign of abating, a growing number of people are getting endocarditis from injecting the drugs — sometimes repeatedly if they continue shooting up. Many are uninsured, and the care they need is expensive, intensive and often lasts months. All of this has doctors grappling with an ethically fraught question: Is a heart ever not worth fixing?…’
‘The Negro Motorist Green Book was a series of annual guides for African-American drivers and holiday-makers who wanted to know where they could find gas-stations, restaurants and hotels that would serve them and which “sunset towns” they should avoid on pain of violence from corrupt, racist law-enforcement.
London crawling:
Schadenfreude Dept.:
Join the elite who rule the world covertly:
‘Researchers report we may have evolved to depend on our gut bacteria to aid normal brain function, and changes in our microbiome could have effects on our behavior….’
‘Charles Neville — who usually performed in a beret and a tie-dyed shirt, with an irrepressible smile — was the band’s jazz facet, reflecting his decades of experience before the Neville Brothers got started. His soprano saxophone was upfront on the Nevilles’ “Healing Chant,” which won a Grammy Award as best pop instrumental in 1990….’
Trump impeachment:
One theory of human evolution states that our ancestors began eating meat about 2 million years ago, whose caloric and fat density allowed the enlargement and development of their brains.
When humans die out because of climate change, they may be the biggest and most widespread animal left, thereby inheriting the planet.
The dark history of ‘America first’:
A look at the available evidence:
‘Despite seeing it millions of times in pretty much every picture book, every novel, every newspaper, and every email message, people are essentially unaware of the more common version of the lowercase print letter “g,” Johns Hopkins researchers have found.
‘For Europeans, April Fools hearkens back to the transition to the Gregorian calendar in the sixteenth century. The pre-Gregorian calendar had ended the year near the end of March, coinciding with the beginning of spring. With the new Gregorian calendar, the beginning of the year was moved to January. The calendar change was slow to take hold and there was resistance to it, but those who continued celebrating the new year at the beginning of April, old style, were ultimately shamed as “fools.”…’
‘When you can’t get to sleep at night, you might explain it to someone as your brain not being able to shut off.
‘How do blind people experience psychedelic drugs? This is the topic of an interesting, but unusual, paper just out in Consciousness and Cognition.
‘With the death of the last male northern white rhino last week, the world was reminded that yet another charismatic animal is functionally extinct because of humans. But in the future, because of synthetic biology, extinction may not be forever. And the northern white rhino could be the animal that pioneers a suite of new technologies that get us there….’
‘Self-help millionaire Tim Ferriss is a fraud. But his success says a lot about modern capitalism and its discontents….
‘A beautiful photo-book about endangered animals comes with a wake-up call…’
‘Some people on DMT say they meet aliens, demons, and even elves. It’s a common enough experience that Johns Hopkins wants to know more….’
Newfound ‘organ’ had been missed by standard method for visualizing anatomy
‘Ignored amidst all of his other scandals, Trump’s mob ties are as deep as they are unprecedented….’
‘Bolton has recently called for war with both Iran and North Korea….’
‘That’s right, I’ll say it, take a long strange trip. Come back in 346 hours and tell us what you found….’