‘cuts heart attacks by 80%’:
“A once-a-day pill for everyone over 55 could undo some of the ill-effects of our sedentary, high-cholesterol, western lifestyle and slash the rate of strokes and heart attacks by more than 80%, doctors said yesterday.
The bold concept of the Polypill, made of a combination of six different drugs, was launched in the British Medical Journal by its inventors with the claim that it could have ‘a greater impact on the prevention of disease in the western world than any other known intervention’.
The editor of the Journal, Richard Smith, piled on the hyperbole, writing that: ‘It’s perhaps more than 50 years since we published something as important as the cluster of papers from Nick Wald, Malcolm Law and others.'” Guardian/UK
Curiously, the Guardian article does not go into precise detail about the proposed content of the PolyPill. This Washington Post article does:
The pill would include aspirin because it has been shown to reduce the risk for heart attacks, probably by limiting the formation of dangerous blood clots. It would also include the nutrient folic acid, which reduces a substance in the blood known as homocysteine, which has been strongly linked to heart disease.
Including one of the cholesterol-lowering drugs, known as statins, which millions already use safely, would be crucial. And finally, the polypill would include three different types of blood-pressure lowering drugs at half the usual doses. It would use three so that each could be given at the lower dose, minimizing side effects like lethargy.
All the components could be used in generic form, minimizing the cost, Wald said.
Under the proposal, the drug would be given to anyone with a known risk factor for cardiovascular disease and everyone age 55 and older, the age when most people begin to develop cardiovascular disease, Wald said. One of the most controversial aspects is that the pill would be given to people without first testing their blood pressure or cholesterol levels.