via Sprudge Coffee:

‘As reported by Scientific American, many biohackers are using the supplement due to its ability to rapidly flush caffeine out of the body, thus mitigating the length of the effects. Rutaecarpine works by causing the liver to produce more of the enzyme CYP1A2, which breaks down caffeine. Thus the more CYP1A2 you have, the faster you can nullify caffeine’s effects.

The issue is that CYP1A2 is also responsible for turning acetaminophen, also known as Tylenol, and converting it to NAPQI, a toxic metabolic byproduct that could potentially damage the liver. Damage that would only occur otherwise through an overdose of acetaminophen.…’