‘Despite incredible advances in biomedicine, a true cure for HIV has remained elusive. Antiretroviral drugs have transformed HIV into a manageable condition instead of a death sentence. But HIV permanently integrates into the genome of an infected cell and then hides, dormant, in the body, making it nearly impossible to eradicate. Since the 1980s, researchers have been hopeful that gene therapy, in which the body’s genetic material is altered, could provide a new route to treating HIV, and maybe even a cure. Brown’s case made many in the field optimistic, but scientists are still stumped as to exactly how his cure worked.
A new study published Thursday in PLOS Pathogens shows a new potential route to curing HIV—though it also highlights the extreme difficulties facing researchers….’