How did enlightenment thinkers distinguish between ‘drugs’ and ‘medicines’? And how should we? ‘…[T]he same novel sensory effects that made substances such as tobacco, opium and cannabis desirable to global consumers also made them fascinating for the earliest experimental scientists. But what did those drugs mean – for them, and for us? How did our modern binary between ‘illicit drug’ and ‘valuable medicine’ come into being?’ – Benjamin Breen (Aeon).