White House Is Leaning on Interim Appointments

“With only 15 months left in office, President Bush has left whole agencies of the executive branch to be run largely by acting or interim appointees — jobs that would normally be filled by people whose nominations would have been reviewed and confirmed by the Senate. In many cases, there is no obvious sign of movement at the White House to find permanent nominees, suggesting that many important jobs will not be filled by Senate-confirmed officials for the remainder of the Bush administration. That would effectively circumvent the Senate’s right to review and approve the appointments.” (New York Times )

Progress Cited in Alzheimer’s Diagnosis

Preliminary but exciting progress towards a lab test for Alzheimer’s Disease, which to now is only diagnosed impressionistically (until post-mortem):

“The researchers gathered more than 200 blood samples from people with Alzheimer’s and those without. Using 83 of the samples, they measured the abundance of 120 proteins involved in cell signaling and found they could distinguish the Alzheimer’s samples from the controls using 18 of the proteins.

They then tested their 18-protein signature on an additional 92 samples. The tests agreed with the clinical diagnosis about 90 percent of the time.

Perhaps most intriguing were the results of the test on 47 blood samples taken from people with mild cognitive impairment, a minor loss of memory that can be a precursor of Alzheimer’s. The test was able to predict with about 80 percent accuracy whether a patient went on to develop Alzheimer’s two to six years after the blood sample had been collected.” (New York Times )

A Person Could Develop Occult

“There must be a rational explanation for all the supernatural phenomena on television. There must.

Because it is weird, and even a little freaky, that so many shows this season prey on the paranormal. Vampires have day jobs as detectives, store clerks reap souls for the Devil, reporters time-travel to get their stories straight, cheerleaders walk through fire and people of all kinds talk to dead people, sometimes quite chattily. ” (New York Times )

Unraveling the Knots of the 12 Tones

“…[T]he invention of the 12-tone system was arguably the most audacious and influential development in 20th-century music. Its impact can be heard today in works far removed from the knotty scores of composers like Milton Babbitt, Pierre Boulez, Charles Wuorinen and its other formidable practitioners during its heyday in the third quarter of the last century. Elements of 12-tone style turn up even in Broadway shows and film scores. Yet an overwhelming majority of music lovers have no idea what the technique is, what exactly the music sounds like or what the fuss was all about.” (New York Times )