Silent Minds

Jerry Groopman, one of my favorite physician-writers, on persistent vegetative state and related conditions. PET and fMRI scanning of some patients shows they are still having complex cognitive functions. Unlike Terry Schiavo’s supporters’ assertions, the issue is not that we are wrong about what goes on in a vegetative state. It is that some, or even many, patients are misdiagnosed:

“According to several American and British studies completed in the late nineties, patients suffering from what is known as “disorders of consciousness” are misdiagnosed between fifteen and forty-three per cent of the time. Physicians, who have traditionally relied on bedside evaluations to make diagnoses, sometimes misinterpret patients’ behavior, mistaking smiling, grunting, grimacing, crying, or moaning as evidence of consciousness. A neuroscientist showed me a video on the Internet of Terri Schiavo, the Florida woman who spent fifteen years in what most doctors agree was a vegetative state—tests revealed almost no activity in her cortex—and whose death, in 2005, provoked fierce debate over the rights of severely brain-damaged patients. (Schiavo died after the Supreme Court rejected her parents’ appeal of a judge’s decision approving her husband’s request that her feeding tube be removed. An autopsy showed extensive brain damage.) In the video, a man’s voice can be heard praising Schiavo for opening her eyes in response to his instructions, and the neuroscientist told me that he was impressed until he muted the sound. “With the sound off, it is clear that her movements are random,” the neuroscientist said. “But, with the voice-over, it is easy to make a misdiagnosis.” (The prognosis for patients such as Schiavo, who suffered brain damage owing to oxygen deprivation following cardiac arrest, is much worse than for those who suffer brain damage as the result of a head injury.)” (The New Yorker)