“Obsessed with reruns of the TV sitcom Friends? Well then you probably have at least one “Jennifer Aniston cell” in your brain, suggests research on the activity patterns of single neurons in memory-linked areas of the brain. The results point to a decades-old and dismissed theory tying single neurons to individual concepts and could help neuroscientists understand the elusive human memory.

“For things that you see over and over again, your family, your boyfriend, or celebrities, your brain wires up and fires very specifically to them. These neurons are very, very specific, much more than people think,” says Christof Koch at the California Institute of Technology in Pasadena, US, one of the researchers.

In the 1960s, neuroscientist Jerry Lettvin suggested that people have neurons that respond to a single concept such as, for example, their grandmother. The notion of these hyper-specific neurons, coined “grandmother cells” was quickly rejected by psychologists as laughably simplistic.

But Rodrigo Quiroga, at the University of Leicester, UK, who led the new study, and his colleagues have found some very grandmother-like cells. Previous unpublished findings from the team showed tantalising results: a neuron that fired only in response to pictures of former US president Bill Clinton, or another to images of the Beatles…” (New Scientist)