The first schizophrenia gene is discovered:
“A gene variant contributing to the cause of catatonic schizophrenia in a large pedigree was discovered by scientists of the
Julius-Maximilians-University of Wuerzburg, Germany. The variant was detected when a group of psychiatrists, geneticists, and neuroscientists
around Klaus-Peter Lesch and Jobst Meyer at the Department of Psychiatry and Psychotherapy investigated genes on human chromosome 22 to
elucidate the genetic background of dominantly inherited catatonic schizophrenia, which is characterized by acute psychotic episodes with
hallucinations, delusions, and disturbed body movements. The protein encoded by this gene, which has been designated WKL1, shares some
features with ion channels. Ion channel proteins are located in the cell membrane and assist transportation of electric currents along neurons.
Mutations in the potassium channel KCNA1, another ion channel which is remotely related to WKL1, cause episodic ataxia, a rare movement
disorder lacking psychotic episodes.” EurekAlert!
