Tests dash hopes of rapid production of bird flu vaccine: “The results of first large-scale trials of a low-dose vaccine against H5N1 bird flu have been announced – and they are unexpectedly disappointing.” (New Scientist) Even with the addition of an adjuvant chemical to stimulate the immune system, low-dose inoculation with H5N1 virus raises measly immune responses. The lower the dose of virus that can be used, the more doses of vaccine could be produced rapidly to cope with a spreading worldwide epidemic.